At Origin, patients and caregivers come first

Origin’s Compassionate Use/Expanded Access Policy

Currently, Origin does not have a formal expanded access program in place and considers requests for expanded access only on a case-by-case basis. Inquiries regarding expanded access may be sent to You can expect acknowledgment of your message within 5 business days. Patients seeking to enroll in clinical studies should visit for information regarding ongoing studies and current study site locations.

Urgent question about investigational therapy?*
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  1. The safety and efficacy of fosdenopterin hydrobromide have not been established. There is no guarantee that fosdenopterin hydrobromide will receive health authority approval or become commercially available in any country for the uses being investigated.

Our commitment to patients and caregivers

At Origin Biosciences, we strive to establish and build relationships with patients and caregivers in the molybdenum cofactor deficiency (MoCD) community. We are committed to conducting these relationships with honesty, integrity, and transparency. Origin respects the independence of patient organizations and the unique perspective of every advocate, patient, and family member. We actively seek the viewpoints of patients, families, and advocates in the drug development process by listening and learning from their unique experiences.

Keeping support connections strong

Origin maintains strong partnerships with organizations and groups that are committed to supporting those affected by MoCD Type A.

Child Neurology Foundation

Offers programs, initiatives, and annual projects that provide education and support for those living with neurologic conditions. Visit

Metabolic Support UK

Provides free, impartial, and confidential advice and information on diagnosis, treatment, and beyond. Visit

National Organization for Rare Diseases (NORD)

Visit for information on rare diseases, including videos, resources, and information on clinical trials and other research.

Click to view videos on rare diseases.

Global Genes

Connects, empowers, and inspires the rare disease community, offering resources, programs, and sponsored events. Visit

Eurordis (Rare Diseases Europe)

Seeks to help those living with rare diseases through advocacy, research, and networking. Visit

Think you see MoCD?
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San Francisco Office

75 Federal Street
San Francisco, CA 94107
Phone (650) 391.9740


Boston Office

75 Park Plaza
Boston, MA 02116
Phone (650) 391.9740